![]() ![]() The first study on PEEK’s cytotoxicity was completed in 1987 and published in the Journal of Material Science Letters. PEEK’s cytotoxic potential has been extensively studied, and the material has been proven safe in this regard. Cytotoxicity – Cytotoxicity refers to a material’s potential to cause cell injury or death, and it is the bare minimum that a biomaterial must offer. Specifically, this is what medical literature has to say about PEEK’s safety:ġ. There’s plenty of evidence that shows PEEK passes the test in every category. ![]() To be considered biocompatible, a material cannot demonstrate any cytotoxicity or genotoxicity, and it must be immunogenic. Medical facilities and practitioners trust the biomaterial for their patients. So positive, in fact, that PEEK is being explored for many other roles in medicine. In addition to extensive research into the material, PEEK has been incorporated into spinal fusion cages for 20 years, and the results have been overwhelmingly positive. ![]() What is the extent of PEEK’s biocompatibility?Īmong biomaterials, no trait is more important than biocompatibility, and PEEK’s has been proven beyond a doubt. These studies have looked into PEEK’s biocompatibility from a cytotoxic, genotoxic and immunogenic angle, with few concerns being noted. There is plenty of safety research to support this approach, with some studies dating back more than two decades. In fact, PEEK is so biocompatible that it can be used in the spine, close to the heart, in the oral cavity and around damaged bone. Even long-standing biomaterial options like titanium can have issues once implanted in the body, but PEEK is showing few limitations on this front. PEEK isn’t the first material to display total biocompatibility, but few materials are as safe and versatile as the high-performance polymer. PEEK’s biocompatibility has been demonstrated through years of research and patient use. ![]()
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